Publication / Source: Bioanalysis 3(12)
Authors: Joshi E
“I found this book to be a unique set of examples that clearly articulate many of the dilemmas researchers in the field face when working to bring new medicines to the patient.”
Over the past century, the pharmaceutical industry has been challenged by both social and economic pressures to optimize the drug-discovery process in order to improve the efficiency by which new drugs are discovered and developed. This endeavor has cultivated a large pharmaceutical industry whose individual members have employed a variety of differing strategies centered on one goal: rapid delivery of medications to the patient. Central to this enterprise has been establishing a link between the in vitro potency, physicochemical properties and absorption, distribution, metabolism, excretion and toxicity (ADME/T) characteristics of a drug candidate.