Capillary plasma separation microsampling devices: a solution for dried blood spot limitations in clinical testing
Bondan AP & Linden R | Bioanalysis, 15(11), 591-593, (2023)
Keywords: • capillary microsampling • clinical chemistry • dried blood spots • dried plasma • microsampling devices • therapeutic drug monitoring
Dried blood spot (DBS) testing has gained significant popularity in the field of bioanalysis, particularly in therapeutic drug monitoring applications. A PubMed search using the term “dried blood spot testing”, restricted to 2002–2012, produced 99 results, whereas a search for 2013–2022 resulted in 1094 results.
A growing understanding of the characteristics of DBS sampling and testing has led to significant advancements in the use of this biomaterial for measuring the concentrations of health biomarkers, drugs and metabolites. Among the potential advantages of DBS testing, the most noteworthy are the possibility of remote and home sample collection; ease of storage and transportation, typically at room temperature; and reduced biohazard.
