In the Zone: cell-based assays
Cell-based assays can be utilized throughout the drug development process for a faster translation to clinical trials. By utilizing cell cultures as model systems, cell-based assays provide an experimental tool for the quantification of various cellular activities including cytotoxicity, biological activity and off-target interactions with drugs and therapeutics. Cell-based assays can accelerate the drug discovery process by delivering the ideal drug candidate analyzed in the most relevant biological environment.
INFOGRAPHIC
An Overview of Cell-Based Assays – In this all-new infographic, we will give a broad overview of the current landscape of cell-based assays, their market worth and growth, challenges that continue to be faced within the bioanalytical community and future solutions working towards ways to save on costs, time and resourcing.
WEBINAR
Development of a cell-based assay for dual purposes: to support drug potency and immunogenicity characterization – During drug development, cell-based assays may be used for multiple purposes, including early proof-of-concept to identify biological activity of the drug product and to determine whether neutralizing anti-drug antibodies are present. Here we present our process to develop cell-based assays that could be used to support both. We will be discussing all critical evaluations and highlighting time and cost savings when developing an assay for both applications.
RESOURCES
Validation of cell-based fluorescence assays: practice guidelines from the ICSH and ICCS
[Video edit by Sandra Kongo-Bacary]
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