Potential of mass spectrometry metabolomics for chemical food safety

This review aims to describe the most significant applications of mass spectrometry-based metabolomics in the field of chemical food safety. A particular discussion of all the different analytical steps involved in the metabolomics workflow (sample preparation, mass spectrometry analytical platform and data processing) will be addressed. Food safety has become a major issue worldwide, and in particular, detecting the presence of toxins, contaminants or residues of chemical substances constitutes a strong consumers demand. Generally all these substances and corresponding metabolites of interest are analyzed using efficient targeted methodologies. However, in some cases these targeted approaches do not allow the detection...