Technology Digest: Pharmaceutical quantification using mass spectrometry: a new wave of technology

Technology Digest covering mass spectrometry techniques, including the SCIEX 7500+.

Various techniques are available for pharmaceutical drug quantification, spanning chromatographic, spectroscopic and mass spectroscopy (MS)-based methods. Among these, MS is considered the gold standard due to its superior sensitivity, selectivity and structural resolution capabilities. MS instruments differ based on their mass analyzers, each using different physical principles to achieve separation and detection and produce an m/z. Here we compare the capabilities of Q-TOF, Orbitrap™ and QqQ systems, and highlight the SCIEX 7500+ QqQ system as a principal platform to support regulated bioanalysis in clinical trials and pharmaceutical development.

This eBook includes:

  • TECHNOLOGY DIGEST: Pharmaceutical quantification using mass spectrometry: a new wave of technology

  • TECH NOTE: Redefine bioanalysis with enhanced robustness on the SCIEX 7500+ system

  • REVIEW ARTICLE: Review on in vivo profiling of drug metabolites with LC-MS/MS in the past decade

  • REVIEW ARTICLE: Biopharmaceutical quality control with mass spectrometry

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