Troubleshooting and Optimization of Bioanalytical Methods for Therapeutic and Endogenous Peptides
This is the final presentation in a series of 3 webinars brought to you by Waters Corporation and Bioanalysis Zone on “Scientists Helping Scientists Meet New Challenges in Pharmaceutical Drug Discovery and Development”. In this webinar Erin E. Chambers of Waters Corporation will discuss “Troubleshooting and Optimization of Bioanalytical Methods for Therapeutic and Endogenous Peptides”.
Topics Covered:
- Identify specific challenges that cause large molecule methods to fail and learn how to identify the nature of the issue and develop an appropriate solution
- Better understand problematic peptides, with specific examples, to highlight challenges such as peptide loss, poor sensitivity, solubility, specificity/selectivity, protein binding, non-specific binding, low extraction recovery, and more
- Learn strategies to characterize a peptide prior to the start of method development and how that information can help streamline the method development process
Panelist’s Biography:
Erin E. Chambers
Principal Applications Chemist
Waters Corporation
Erin Chambers is a Principal Applications Chemist, providing pharmaceutical applications development and support for Waters Applied Technology Group. Erin’s primary role is to support regulated and discovery Bioanalysis, and develop bioanalytical methods for drug molecules, both large and small. She is responsible for sample preparation, mass spectrometry, and LC method development, and also provides customer and in-house training on these topics. Her most recent focus has been on peptide and protein bioanalysis.