Bioanalysis Zone

Stable isotope labeled metabolomics improves identification of novel metabolites and pathways

0

“The recent surge in bioanalytical and bioinformatics methods developed for metabolomics studies have significantly improved our ability to expand isotope-labeling studies … bringing us closer to the promise of a true systems biology understanding of the metabolism for many organisms.”

Metabolomics is a rapidly growing field of postgenomic biology that enables system-wide studies of cellular metabolism. Stable isotope labeling is an established approach for investigation of the dynamics of metabolic pathways. The combination of these two approaches promises to provide a comprehensive understanding of metabolic networks in biological systems. Metabolomics involves the semi-quantitative detection of many small molecules (<1500Da) in a biological system using modern bioanalytical platforms such as NMR, GC–MS, CE–MS and LC–MS.

Click here for the full article.

Share:

Leave A Comment