Video: Antibody drug–conjugates characterization (Waters Corporation)

21 May 2015

This video discusses powerful analytical tools which can be used to interrogate and understand ADCs. In particular, it outlines:

Characterizing ADCs with hydrophobic interaction chromatography
Deriving DAR via native UPLC/MS
Resolving positional isomers by 2D UPLC/MS
Identifying conjugation by peptide mapping

Previous article Next article

											
										11 JAN 2018
																					NEWS
																			
										Publish with us!
									
										26 APR 2016
																					JOURNAL ARTICLES
																			
										Development and validation of HILIC–ESI/MS/MS methods for simultaneous quantitation of several antipsychotics in human plasma and blood
									
										20 MAY 2015
																					GENERAL INTEREST
																			
										Application note: Development of integrated informatics workflows for the automated assessment of comparability for antibody-drug conjugates (ADCs) using LC-UV and LC-UV/MS (Waters Corporation)
									
										2 NOV 2020
																					MS (LC–MS/MS, HRMS, IMS)
																			
										Echo® MS System for high-throughput analysis
									
										28 JAN 2014
																					MS (LC–MS/MS, HRMS, IMS)
																			
										Mass spectrometry imaging for cancer tissue analysis
									
										8 DEC 2016
																					JOURNAL ARTICLES
																			
										2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 2 – Hybrid LBA/LCMS and input from regulatory agencies)