In the Zone: immunogenicity


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INFOGRAPHIC
| PODCAST | RESOURCES

Pathogen immunity has long been determined by antibody-detection assays, however, in many situations, measuring T-cell immunity to specific pathogens can provide physicians with significantly improved clinical utility. Monitoring T-cell immunity is also critical in the development of new therapies as mechanism to assess immunogenicity. T-cell immunity can be measured with a variety of different techniques, each demanding a certain level of expertise, equipment and labor intensity.

In this feature, we explore the key qualities to look for to ensure success when outsourcing immunogenicity assay development and testing. We also explore the methods for – and challenges involved with – T-cell immunity monitoring and assay development.

PODCAST

podcastsT-cell immunity monitoring and assay development: an interview with Steven Kleiboeker

Ahead of his presentation at the  World Vaccine and Immunotherapy Congress (2–5 December, San Francisco; CA, USA), Dr Steven Kleiboeker (Vice-President of Research and Development at Viracor Eurofins BioPharma Services, Kansas City, MO, USA) discusses the methods for – and challenges involved with – T-cell immunity monitoring and assay development. He also discusses the current research focuses at Viracor Eurofins laboratories, the importance of other viral assays and his hopes for the future directions of T-cell immunity assays.

Learn more!
If you want to find out more about T-cell immunity monitoring and assay development, Dr Kleiboeker presented this topic at the  World Vaccine and Immunotherapy Congress (2–5 December, San Francisco; CA, USA) Click here to watch the presentation!

INFOGRAPHIC

INZ CAR-TKey qualities to ensure success when outsourcing immunogenicity assay development

This infographic highlights the key qualities to look for in a CRO to ensure the best results when outsourcing immunogenicity assay development and testing.

 

RESOURCES

Bioanalysis Zone hexagon

Susceptible or immune? CMV T-cell immunity accurately predicts patient status

Immunogenicity: an interview with Eric Bonner

2018 White Paper on Recent Issues in Bioanalysis: focus on immunogenicity assays by hybrid LBA/LCMS and regulatory feedback