Incurred sample reanalysis: enhancing the Bland–Altman approach with tolerance intervals


This article describes the need for incurred sample reanalysis and suggests that the combination of a Bland?Altman plot and tolerance intervals can provide a visual evaluation of method performance. It also shows how the proposed combination is a tool that may be of value in determining minimum sample size. An example dataset is worked through in its entirety so that a reader unfamiliar with the topic can gain sufficient information to analyze their own data. Related topics include the generation of 66.7% tolerance factors, comparison of mean-normalized and log differences and the use of probability plots to evaluate error distributions....

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