In this Bioanalysis Zone interview, Zamas Lam (QPS; DE, USA) discusses various methods that can be used to quantify oligonucleotide drugs. Zamas also explains the progress that has been made to regulate and standardize oligonucleotide analysis in recent years, before sharing his thoughts on where the field will be in 5–10 years’ time.
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Analytical approaches for quantitative determination of therapeutic oligonucleotides from biological samples
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