Bioanalysis Zone

Improving the sensitivity and specificity of a bioanalytical assay for the measurement of certolizumab pegol


Aim: In order to evaluate placental transfer of certolizumab pegol (CZP), a more sensitive and selective bioanalytical assay was required to accurately measure low CZP concentrations in infant and umbilical cord blood. Results & methodology: A new electrochemiluminescence immunoassay was developed to measure CZP levels in human plasma. Validation experiments demonstrated improved selectivity (no matrix interference observed) and a detection range of

To view restricted content, please:

Leave A Comment