In this ‘Ask the Experts’ feature we will be discussing the use of high-resolution mass spectrometry (HRMS) with a number of leading experts across the field. The series will explore the role of HRMS, address the advantages and current challenges, as well as investigate the future of the technology.
HRMS has been available for a long time; originally it was applied in qualitative applications, however, the introduction of spectrometers with improved mass resolution over wider mass ranges, has allowed for the application of HRMS in quantitative workflows.
In the clinical setting, HRMS is increasingly being adopted due to its ease of operation, reasonable cost and maintenance. HRMS can also be combined with qualitative exploration of data in the small-molecule field.
To address questions raised in our previous Spotlight on quantitative HRMS and to investigate how the field has progressed over the last 2 years, key figures from pharma, CROs, biotech and academia share with us their experiences and thoughts on quantitative HRMS, giving our members a 360° opinion piece.