Bioanalysis Zone

Parallel Artificial Liquid Membrane Extraction of Psychoactive Analytes-a novel approach in therapeutic drug monitoring


Aim: Liquid–liquid extraction is widely used in therapeutic drug monitoring of antipsychotics, but difficulties in automation of the technique can result in long operational time. In this paper, parallel artificial liquid membrane extraction was used for extraction of serotonin– and serotonin–norepinephrine reuptake inhibitors from human plasma, and an approach to automate the technique was investigated.

Results: Eight model analytes were extracted from

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Click here to find out more about author, Astrid Gjelstad (University of Oslo), in our author’s perspective interview series:

Untitled design(2)“I am currently an Associate Professor at the School of Pharmacy, University of Oslo (Norway). I received my PhD degree in 2009 and completed my doctoral training also at the University of Oslo. My academic field of interest is development of new microextraction technologies based on artificial liquid membranes for rapid and selective isolation of drugs and peptides from small amounts of biological matrices. Another research focus comprises new inventions in the area of dried blood spots (DBS). At the moment, I am also holding a part-time position as medical advisor at Anti-Doping Norway (Oslo, Norway).”


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