Bioanalysis Zone

AAPS: day one highlights


New BioContinuum™ Platform launched by MilliporeSigma to advance biotherapeutic drug manufacturing

Naamah Maundrell (Future Science Group)

MilliporeSigma (MA, USA) have launched their new BioContinuum™ Platform at the American Association of Pharmaceutical Scientists PharmSci 360 conference (4—7 November 2018; Washington DC, USA).

BioContinuum Platform features process intensification technologies to obtain incremental process benefits now, with a mind to the continuous process of the futureMilliporeSigma (MA, USA) have launched their new BioContinuum™ Platform at the American Association of Pharmaceutical Scientists PharmSci 360 conference (4—7 November 2018; DC, USA). The new platform is hoped to improve biotherapeutic drug manufacturing through simplified plant operations and improved efficiency.

Udit Batra, CEO of MilliporeSigma commented: “MilliporeSigma’s new, adaptive platform of products, applications and expertise will allow customers to bring new therapies to patients in need, faster and more cost-effectively than ever before. Our unique and holistic approach to next-generation bioprocessing allows us to realize the benefits of process intensification throughout the entire process, not gained by focusing on one area at a time.”

PrintThe new technology aims to connect separate manufacturing steps, enabling continuous bioprocessing, which could reduce manufacturing cost by up to 50%. MilliporeSigma also added to the purification of the BioContinuum™ Platform by introducing the expanded Pellicon® Single-Pass Tangential Flow Filtration product. The filtration product improves the capacity and productivity of the purification process.

Batra concluded: “We are advancing this industry by improving process economics without sacrificing titer or product quality while minimizing waste, energy consumption and raw material use.”

Images credit: MilliporeSigma

Thermo Fisher Scientific introduce software for the identification and characterization of small molecules and fragments at AAPS

Georgi Makin (Future Science Group)

Thermo Fisher Scientific (MA, USA) have announced the launch of their Thermo Scientific Mass Frontier 8.0 software, which can help scientists in overcoming challenges associated with the identification and characterization of small molecules and their fragments by efficiently translating complex data into sharable knowledge.

Thermo Scientific Orbitrap IDX_imageFollowing 20 years of collaboration with HighChem (Bratislava, Slovakia), the software is capable of analysing MSn mass spectrometric data produced during the identification and structural characterization of small-molecule unknown compounds and their fragments.

“Small-molecule unknown compound identification and analysis using mass spectrometry generates large quantities of complex data, which is labor intensive and time-consuming to process and confidently turn into knowledge,” explained Iain Mylchreest, Vice President, Thermo Fisher Scientific. “Through its powerful algorithms and fully-curated knowledge databases of spectral and fragmentation data that covers 95% of all published fragmentation pathways, Mass Frontier 8.0 software accelerates small-molecule characterization.”

“We have been using the Mass Frontier software for over 10 years in the UC Davis Fiehn Lab and think every mass spectrometrist should have a copy of Mass Frontier software,” continued Tobias Kind (University of California, Davis; CA, USA). “The functionality of mzCloud integration, as well as the look and design, is well-organized and intuitive.”

You can find out more by visiting Thermo Fisher Scientific at AAPS at booth #418, or by visiting the website.

Source: Thermo Fisher Scientific press release
Image credit: Thermo Fisher Scientific


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