Challenges of developing a bioanalytical method for a macrolide immunosuppressant compound by LC–MS/MS

Marie-Pierre Taillon holds a Bachelor of Science in Biochemistry. She is a senior scientist in method development at Algorithme Pharma, a CRO located in Laval, Canada. She has been working in the bioanalysis industry for the past 11 years where she became an expert in method development, especially in the LC–MS/MS field. Her experiences have led her to conduct robust and effective method development of bioanalytical assays. Marie-Pierre has acquired over the years an expertise with the ‘-limus’ compounds (e.g., tacrolimus, sirolimus and everolimus) and other complex molecules. The quantification of tacrolimus in human whole blood was developed by LC–MS/MS...