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Stakeholders in academia, industry, and CROs are com

mitted to building a complete platform to develop therapies for rare diseases, and they are using their combined expertise and resources to get there. “There is a continual push amongst people who work in rare diseases to bring [treatments] forward quicker,” notes Dr Martin Mackay, PhD, the former Head of Research and Development at Alexion Pharmaceuticals.

The unique capabilities of CROs, like Charles River, allow the design of customized rare disease studies using pre-existing methods, considerably increasing the efficiency and effectiveness of novel therapeutic development.

Thousands of rare diseases still lack novel therapies. But the creation of a robust collaborative ecosystem will ultimately facilitate efficient drug development for the patients who desperately need it.

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Watch this Panel discussion on new technology integration in bioanalytical workflows

About Us

With a commitment to scientific excellence, Charles River provides industry-leading GCP and GLP laboratory services to support our clients’ drug development, from discovery to the clinic. Whether clients need stand-alone solutions or a package tailored to meet their needs, we apply our in-depth knowledge of biomarkers, traditional NCEs, proteins, and large molecules to optimize their discovery and development programs to accelerate the journey to market. Our focus on partnership ensures our clients receive the very best in personalized service and support. From compound screening, rapid custom PK and immunogenicity assay development, validation and sample analysis to on-time reporting, we can support our clients’ research and protect their investment, every step of the way.

The Laboratory Sciences team at Charles River balances scientific integrity, cost-effectiveness and regulatory compliance within the most stringent of time frames to deliver comprehensive support throughout the entire drug discovery and development process. Our global capabilities ensure that you have the resources necessary to handle all of your laboratory support needs, or simply to supplement your in-house capabilities.

We believe in remaining at the forefront of laboratory technology and have made significant investments in highly trained chemists, facilities and instrumentation to produce rapid and reliable data.
Areas of expertise include:

• Bioanalysis
• Compound screening and lead optimization
• Drug metabolism and pharmacokinetics (DMPK)
• Clinical sample kits
• Immunology
• Molecular biology
• Biomarker assay development, validation and sample analysis
• Formulation development, pharmacy and analytical chemistry
• Genetic toxicology
• In vitro services

Email: [email protected]
Telephone: 1-877-274-8371
Corporate Head Quarters:
251 Ballardvale Street
Wilmington, MA 01887
Global Facilities located in the United States, Canada, UK, and Europe