Mass spectrometry for the identification of drug candidates against antibiotic-resistant bacterial proteins

A team of researchers from the Miami University (OH, USA) have optimized native state mass spectrometry to identify the best drug candidates against resistant bacteria. Antibiotic resistance has been a growing problem in the last century, leading to a rise in bacterial infections, which can no longer be treated with current antibiotics. The United States alone sees 2.8 million individuals diagnosed with an antibiotic-resistant bacterial infection. According to the Centers for Disease Control and Prevention (GA, USA), 35,000 individuals die every year due to bacterial infections resistant to antibiotic treatment (2019). “One method of combatting antibiotic resistance is using a...