The potential application of electromembrane extraction for the analysis of peptides in biological fluids


“…EME is compatible with different biological fluids, including human plasma and whole blood, which are relevant samples for peptide analysis. Therefore, it is highly relevant to investigate EME for extraction of peptides.” Electromembrane extraction (EME) is a new analytical sample preparation technique and was described for the first time in 2006 [1]. EME has mainly been used for extraction of small drug substances and environmental pollutants, but recently EME has also been tested for extraction of peptides and amino acids [2–8]. In EME, charged analytes (e.g., drugs, environmental pollutants or peptides) are first extracted from the sample (aqueous) into a...

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