Original Publication Date: 1 June, 2018
Publication / Source: Bioanalysis (Ahead of print)
Authors: Bults P, Meints M, Sonesson A, Knutsson M, Bischoff R, van de Merbel NC.
Aim: Protein quantitation by digestion of a biological sample followed by LC–MS analysis of a signature peptide can be a challenge because of the high complexity of the digested matrix.
Results/methodology: The use of LC with high-resolution (quadrupole-TOF) MS detection allowed