Original Publication Date: 12 December, 2019
Publication / Source: Bioanalysis 11(22)
Authors: Donaldson D, Purushothama S, David E, King K, Huang S, Mehta DS, Stevenson LF
In this Research Article, published by Bioanalysis, investigators from Biogen (MA, USA) and Stat4ward LLC (PA, USA) describe their re-evaluation, in singlet, of data from five pharmacokinetic assay validations and five clinical and preclinical studies, originally run in duplicate. The results of the study confirm that well-developed ligand-binding assays (LBAs) produce comparable data whether evaluated in singlet or duplicate.