Micro total analysis systems in biopharmaceutical process development


“To fulfill the promise of micro total analysis systems in the biopharmaceutical industry, it is important to bridge academic advancements with industry needs through collaborations of scientists from academia, instrument vendors and industry laboratories.” Micro total analysis systems (µTAS), better known as ‘lab-on-a-chip’ devices, are miniaturized devices with integrated functionalities including sample loading, sample treatment, separation and detection. A wide variety of applications have been reported using µTAS, from DNA sequencing to protein purity analysis, from cell cultivation to immunoassay, from diagnosis to drug screening and development. Some recent reviews are available on µTAS [1] and their applications in drug...

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