KCAS Bio

KCAS Bio is a top-tier global contract research organization (CRO) that has 45 years of experience with both large pharma and biotech sponsors, providing comprehensive bioanalytical drug development services from early discovery through registration. We have supported more than 300+ FDA approved drugs on the market, developed 5,000+ proprietary and non-proprietary assays to date, and undergone 18 FDA audits with no major findings. Our presence in multiple locations throughout the US and Europe – and with a strategic alliance in Australia – allows us to serve sponsors globally with bioanalytical, biomarker, immunogenicity, cellular and molecular assay services along with clinical kitting and sample management. With the expertise, capacity and flexibility sponsors require, we can fulfill our purpose, which is to help accelerate the discovery and development of life-changing drugs smoothly, safely and sustainably.

KCAS  Bio specializes in the following services:

Bioanalysis

• Pharmacokinetics/ Toxicokinetics:
  • LC-MS/MS, Hybrid LC-MS/MS, LBA, qPCR, ddPCR
• LNPs:
  • LC-MS/MS, Hybrid LC-MS/MS
• Receptor occupancy:
  • Flow cytometry
• Immunogenicity/ADA:
  • LBA
• Biodistribution:
  • qPCR, ddPCR
• Neutralizing antibodies assays:
  • Cell-based, plate based
• Dose formulation analysis
  • SEC, UPLC

Pharmacodynamics

• Primary endpoints
• Functional assays
• Secondary endpoints/ exploratory assays

Biomarkers

• Soluble biomarkers:
  • LBA, qPCR, ddPCR, LC-MS/MS, MSD
• Cellular biomarkers:
  • ELISpot, flow cytometry, qPCR, ddPCR, single-cell proteomics

Support

• Formulation analysis
• Sample kits (clinical/non clinical)
• Bio-repository

Learn more at www.kcasbio.com or follow us on twitter @KCASBio

Website:
www.kcasbio.com

Email:
[email protected]

Telephone:
913-248-3000

Address:
10830 S Clay Blair Blvd
Olathe, Kansas
66061
USA