Join LGC scientists in the grudge match debate direct from Cambridge (UK) to decide the new king of quantitation.
Browsing: Spotlight Resources
This application note from Waters discusses a robust and reliable IA-LC-HRMS method for the qualitative analysis and quantification of ado-trastuzumab emtansine (T-DM1, Kadcyla™).
High-resolution mass spectrometry: an essential tool for DMPK studies of novel peptide-based modalities
In this editorial Simone Esposito (IRBM, Italy) explores how HRMS has become a well established alternative to multiple reaction monitoring for DMPK profiling and discusses the use of HRMS for DMPK studies of nove peptide-based modalities.
A collection of helpful answers to the most frequently asked questions concerning the use of high-resolution mass spectrometry (HRMS) in drug metabolism and pharmacokinetics (DMPK).
This poster from SCIEX (Warrington, UK) reports the use of an immunoaffinity high-resolution accurate mass assay as a complimentary analytical technique for signature peptide quantification.
This presentation from SCIEX (Warrington, UK) explores why we need high-resolution accurate mass spectrometry quantification, discussing topics ranging from the desire for higher selectivity in complex matrices to the need to analyze multiple charge states and fragment ions.
In this series of presentations, LGC (Cambridge, UK) explores whether high resolution mass spectrometry (HRMS) can challenge the ‘Gold Standard’ triple quadrupole mass spectrometer for quantitative bioanalysis within the CRO environment.
In this series of short, recorded presentations a team from Waters (MA, USA) discuss fundamental and practical details regarding large molecule quantification.
As part of our Spotlight on LBA, we carried out a survey to gain an insight into the trends, challenges and developments associated with this technique. We would like to thank everyone who was able to share their thoughts by taking part in the survey – you can see the results below in our infographic.
In this interview, Hanna Ritzén (Mercodia; Uppsala, Sweden) provides an insight into her recent article on classification of commercial LBA kits for biomarkers, and why this area of bioanalysis is important.